Objective: To optimize the conditions of supercritical fluid extraction (SFE) for curcumin in Curcuma longa.
Method: Optimum extraction conditions were studied by orthogonal tests. The extracts were analyzed by HPLC.
Result: The optimal extraction conditions were pressure 25 MPa, temperature 55 degrees C, static time 4 h, dynamic time 5 h, flow rate of CO2 3.5 L x min(-1), co-solvent ethanol 30% (mL x g(-1)).
Conclusion: It is feasible to extract curcumin by SFE.