Effect of different intensities of swimming exercise on testicular oxidative stress and reproductive dysfunction in mature male albino Wistar rats

Indian J Exp Biol. 2004 Aug;42(8):816-22.

Abstract

Swimming exercise for 1, 2 and 3 hr for 5 days/week for consecutive 4 weeks, results in a significant reduction in testicular, epididymal, prostetic, seminal vesicle somatic indices; epididymal sperm count, sperm motility; preleptotine spermatocytes, mid pachytene spermatocytes and stage 7 spermatids; plasma levels of testosterone, luteinizing hormone; testicular delta5, 3beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase; testicular superoxide dismutase, catalase, glutathione peroxidase, glutathione-s-transferase and glutathione along with significant elevation in malondialdehyde in male albino rats. However, no significant change was noted in final body weight, spermatogonia-A and plasma level of follicle stimulating hormone. The results that oxidative stress develops with the increasing of exercise intensity, which may interfere in male reproductive activities.

MeSH terms

  • Animals
  • Antioxidants / metabolism
  • Genitalia, Male / anatomy & histology
  • Male
  • Organ Size
  • Oxidative Stress
  • Physical Exertion / physiology*
  • Rats
  • Rats, Wistar
  • Reproduction / physiology*
  • Sperm Count
  • Sperm Motility
  • Spermatogenesis / physiology
  • Steroids / blood
  • Swimming / physiology
  • Testis / anatomy & histology
  • Testis / metabolism*

Substances

  • Antioxidants
  • Steroids