Structure confirmation of a bioactive lactone isolated from Otoba parvifolia through the synthesis of a model compound

Francisco A Marques; Cesar A Lenz; Fabio Simonelli; Beatriz Helena L Noronha Sales Maia; Adriana P Vellasco; Marcos N Eberlin

doi:10.1021/np049771x

Structure confirmation of a bioactive lactone isolated from Otoba parvifolia through the synthesis of a model compound

J Nat Prod. 2004 Nov;67(11):1939-41. doi: 10.1021/np049771x.

Authors

Francisco A Marques¹, Cesar A Lenz, Fabio Simonelli, Beatriz Helena L Noronha Sales Maia, Adriana P Vellasco, Marcos N Eberlin

Affiliation

¹ Chemistry Department, Federal University of Paraná, P.O. Box 19081, Curitiba, PR, 81.531-990 Brazil. tic@ufpr.br

PMID: 15568796
DOI: 10.1021/np049771x

Abstract

Synthesis of a model compound 4 structurally related to a bioactive lactone 3 isolated from Otoba parvifolia has been accomplished. The good match between the NMR data of both compounds suggests they have identical bicyclic [3.3.1] carbon skeletons.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fruit / chemistry
Lactones / chemistry
Lactones / isolation & purification*
Lactones / pharmacology
Models, Molecular
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plants, Medicinal / chemistry*

Substances

Lactones