Autonomic dysreflexia manifested by severe hypertension

Med Sci Monit. 2004 Dec;10(12):CS77-9.

Abstract

Background: Autonomic dysreflexia (AD) is a sudden and exaggerated autonomic response to stimuli in patients with spinal cord injuries or dysfunction above the splanchnic sympathetic outflow (T5-T6). Hypertension is a relatively common manifestation of AD.

Case report: We describe a case of a young man with T4-T6 spinal cord tumor who developed severe hypertension before any other clinical feature of AD, leading to a subsequent clinical evaluation and the correct diagnosis. Treatment with labetalol was only partially successful in controlling the elevated blood pressure. Hypertension resolved immediately after bladder decompression.

Conclusions: AD manifested by severe hypertension is uncommon. Bladder decompression appears to be safe and effective for management of hypertension in patients with AD.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antihypertensive Agents / therapeutic use
  • Autonomic Dysreflexia / diagnosis*
  • Autonomic Dysreflexia / etiology
  • Blood Pressure / physiology
  • Drainage
  • Humans
  • Hypertension / diagnosis*
  • Hypertension / etiology
  • Hypertension / therapy
  • Labetalol / therapeutic use
  • Male
  • Spinal Neoplasms / complications
  • Urinary Bladder, Neurogenic / etiology
  • Urinary Bladder, Neurogenic / physiopathology

Substances

  • Antihypertensive Agents
  • Labetalol