Isolation and X-ray crystal structure of a new isoquinoline-N-oxide alkaloid from Calycotome villosa subsp. intermedia

Ali El Antri; Ibtissam Messouri; Mohamed Bouktaib; Rachid El Alami; Michael Bolte; Brahim El Bali; Mohammed Lachkar

doi:10.1016/j.fitote.2004.05.011

Isolation and X-ray crystal structure of a new isoquinoline-N-oxide alkaloid from Calycotome villosa subsp. intermedia

Fitoterapia. 2004 Dec;75(7-8):774-8. doi: 10.1016/j.fitote.2004.05.011.

Authors

Ali El Antri¹, Ibtissam Messouri, Mohamed Bouktaib, Rachid El Alami, Michael Bolte, Brahim El Bali, Mohammed Lachkar

Affiliation

¹ Laboratoire d'Analyses, d'Essais et d'Environnement, Département de Chimie, Faculté des Sciences Dhar Mehraz, Université Sidi Mohamed Ben Abdellah, 30000 Fès, Morocco.

PMID: 15567263
DOI: 10.1016/j.fitote.2004.05.011

Abstract

A new isoquinoline-N-oxide alkaloid was extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome villosa subsp. intermedia. Its structure was established as 1-hydroxymethyl-6,7-dimethoxyisoquinoline-N-oxide (1) by spectroscopic techniques and X-ray diffraction analysis.

MeSH terms

Alkaloids / chemistry*
Crystallography, X-Ray
Fabaceae*
Humans
Isoquinolines / chemistry*
Phytotherapy*
Plant Extracts / chemistry*
Seeds

Substances

Alkaloids
Isoquinolines
Plant Extracts