Modular synthesis of fluorous trialkylphosphines

Gábor Vlád; Frank Richter; István T Horváth

doi:10.1021/ol0480675

Modular synthesis of fluorous trialkylphosphines

Org Lett. 2004 Nov 25;6(24):4559-61. doi: 10.1021/ol0480675.

Authors

Gábor Vlád¹, Frank Richter, István T Horváth

Affiliation

¹ Department of Chemical Technology and Environmental Chemistry, Eötvös University, Pázmány Péter sétány 1/A, H-1117 Budapest, Hungary.

PMID: 15548075
DOI: 10.1021/ol0480675

Abstract

A modular synthetic protocol was developed for the preparation of fluorous trialkylphosphines with a different number of methylene spacers and various lengths of the fluorous ponytails P[(CH(2))(A)R(FX)][(CH(2))(B)R(FY)][(CH(2))(C)R(FZ)] (A, B, C = 3 and 4; X, Y, Z = 4, 6, and 8). [reaction: see text]