Biosynthetic studies on the azinomycins: the pathway to the naphthoate fragment

Christophe Corre; Cyrille A S Landreau; Michael Shipman; Philip A S Lowden

doi:10.1039/b410592c

Biosynthetic studies on the azinomycins: the pathway to the naphthoate fragment

Chem Commun (Camb). 2004 Nov 21:(22):2600-1. doi: 10.1039/b410592c. Epub 2004 Sep 30.

Authors

Christophe Corre¹, Cyrille A S Landreau, Michael Shipman, Philip A S Lowden

Affiliation

¹ School of Biological and Chemical Sciences, University of Exeter, UK.

PMID: 15543299
DOI: 10.1039/b410592c

Abstract

Isotopically labelled intermediates in a proposed biosynthesis of the naphthoate fragment of azinomycin B have been made and successfully incorporated by the azinomycin producing organism.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / biosynthesis*
Antibiotics, Antineoplastic / biosynthesis*
Glycopeptides*
Models, Chemical
Molecular Structure
Naphthalenes / metabolism*
Streptomyces / metabolism*

Substances

Anti-Bacterial Agents
Antibiotics, Antineoplastic
Glycopeptides
Naphthalenes