The special problems of travel during pregnancy have become clinically important as more women are traveling to remote places for business or recreation. Many issues need to be considered in providing health advice to the pregnant traveler. Health practitioners should be able to assist in the careful medical preparations that will ensure the safety of the pregnant woman and fetus during travel. Journey may increase the risk of pregnancy complications because of inherent physiological changes or exposure to environmental hazards and infectious disease. Usually standard interventions are not recommended during pregnancy. In pregnancy, the maternal and fetal benefits of protection from disease and its complications must be carefully balanced against the small, often theoretical risk, of adverse effects following immunization. In some circumstances the best advice may be to postpone travel if effective preventive measures against disease cannot be undertaken and access to medical care is uncertain.