Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformation

Pediatr Pulmonol. 2005 Feb;39(2):185-8. doi: 10.1002/ppul.20116.

Abstract

Recurrent respiratory papillomatosis is the most common neoplasm of the larynx in childhood. Extension into lung parenchyma occurs in less than 1% of patients and has a low risk of malignant transformation. Treatment options for intrapulmonary spread have shown limited success. We describe a case of recurrent respiratory papillomatosis with extensive parenchymal involvement and adenosquamous carcinoma in a 14-year-old girl.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Biopsy, Needle
  • Carcinoma, Adenosquamous / diagnostic imaging
  • Carcinoma, Adenosquamous / pathology*
  • Carcinoma, Adenosquamous / therapy
  • Cell Transformation, Neoplastic* / pathology
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Laryngeal Neoplasms / diagnostic imaging
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / therapy
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / therapy
  • Neoplasm Recurrence, Local / pathology*
  • Papilloma / diagnostic imaging
  • Papilloma / pathology*
  • Papilloma / therapy
  • Radiography, Thoracic
  • Tomography, X-Ray Computed