[The prevention of postoperative deep venous thrombosis with heparan sulfate per os. A controlled clinical study vs. heparin calcium]

M Seccia; M G Bellomini; O Goletti; A Tortora; P Buccianti; M Chiarugi; A Bertolucci; M C Martino; C Macaluso; E Cavina

[The prevention of postoperative deep venous thrombosis with heparan sulfate per os. A controlled clinical study vs. heparin calcium]

Minerva Chir. 1992 Jan;47(1-2):45-8.

[Article in Italian]

Authors

M Seccia¹, M G Bellomini, O Goletti, A Tortora, P Buccianti, M Chiarugi, A Bertolucci, M C Martino, C Macaluso, E Cavina

Affiliation

¹ Cattedra di Chirurgia d'Urgenza, Università degli Studi di Pisa.

PMID: 1553052

Abstract

The paper reports the results of a randomised study carried out on a pool of 100 patients undergoing surgery in order to assess the efficacy and tolerability of orally administered heparan sulfate versus heparin calcium in the prevention of postoperative deep-vein thrombosis. Despite the limits of oral administration, heparan sulfate is indicated in the pharmacological prevention of postoperative deep-vein thrombosis.

Publication types

Clinical Trial
Comparative Study
English Abstract
Randomized Controlled Trial

MeSH terms

Administration, Oral
Drug Tolerance
Fibrinolytic Agents / administration & dosage*
Heparin / administration & dosage*
Heparitin Sulfate / administration & dosage*
Humans
Postoperative Complications / prevention & control*
Surgical Procedures, Operative / adverse effects
Thrombophlebitis / prevention & control*

Substances

Fibrinolytic Agents
calcium heparin
Heparin
Heparitin Sulfate