Abstract
We report on a case of cutaneous infection caused by Alternaria infectoria in a cardiac transplant recipient. A rapid molecular diagnosis was obtained by sequence analysis of the internal transcribed spacer domain of the 5.8S ribosomal DNA region amplified from colonies developed on Sabouraud medium. Treatment consisted of a combination of systemic antifungal therapy, first with amphotericin B and then with itraconazole.
MeSH terms
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Alternaria / classification*
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Alternaria / genetics*
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Alternaria / isolation & purification
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Culture Media
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DNA, Fungal / analysis
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DNA, Ribosomal Spacer / analysis
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Dermatomycoses / microbiology*
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Heart Transplantation / adverse effects*
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Humans
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Male
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Middle Aged
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Mycological Typing Techniques
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Opportunistic Infections / microbiology*
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Polymerase Chain Reaction
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RNA, Ribosomal, 5.8S / genetics
Substances
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Culture Media
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DNA, Fungal
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DNA, Ribosomal Spacer
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RNA, Ribosomal, 5.8S