Artificial life simulation of self-assembly in bacteriophage by movable finite automata

Biosystems. 2004 Nov;77(1-3):151-61. doi: 10.1016/j.biosystems.2004.05.027.

Abstract

This paper presents a model which is based on biological research using the movable finite automata (MFA) on a self-assembly of T4 phage, and exhibits the results of artificial life simulation. In the previous work, Thompson and Goel [Artificial Life, Addison Weley, 1989, pp. 317-340; Biosystems 18 (1985) 23; J. Theor. Biol. 131 (1988) 351] presented the movable finite automata (MFA) which has a capability of moving on finite automata, and simulated on a computer. They were represented individual rectangular boxes, however, the results of simulation was different from real T4 phage. We propose the sphere model as a protein structure, and simulate the self-assembly of the entire structure of the T4 phage on a computer.

Publication types

  • Evaluation Study

MeSH terms

  • Artificial Intelligence*
  • Bacteriophage lambda / chemistry
  • Bacteriophage lambda / physiology*
  • Biomimetics / methods*
  • Computer Simulation
  • Computers, Molecular*
  • Models, Biological*
  • Models, Chemical
  • Virion / chemistry
  • Virion / growth & development*
  • Virus Assembly / physiology*