Abstract
Whether or not yeast cell death is altruistic, apoptotic, or otherwise analogous to programmed cell death in mammals is controversial. However, growing attention to cell death mechanisms in yeast has produced several new papers that make a case for ancient origins of programmed death involving mitochondrial pathways conserved between yeast and mammals.
MeSH terms
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Animals
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Apoptosis / genetics
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Apoptosis / physiology*
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Mammals / genetics
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Mammals / physiology
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Mitochondria / physiology*
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Models, Biological
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Proto-Oncogene Proteins c-bcl-2 / genetics
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Proto-Oncogene Proteins c-bcl-2 / metabolism
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Saccharomyces cerevisiae / cytology*
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Saccharomyces cerevisiae / physiology*
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism
Substances
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Proto-Oncogene Proteins c-bcl-2
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Saccharomyces cerevisiae Proteins