Abstract
An enantioselective addition of titanium phenylacetylide to ketones, promoted by BINOL, is described; this new enantioselective protocol gives high enantiomeric excess (up to 90% ee) with aromatic ketones using a simple procedure without pyrophoric or expensive reagents.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Catalysis
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Hydrocarbons, Aromatic / chemistry*
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Ketones / chemistry*
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Naphthols / chemistry*
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Organometallic Compounds / chemical synthesis*
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Stereoisomerism
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Titanium / chemistry*
Substances
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Alkynes
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BINOL, naphthol
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Hydrocarbons, Aromatic
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Ketones
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Naphthols
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Organometallic Compounds
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Titanium