Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin

Eur J Ophthalmol. 2004 Sep-Oct;14(5):434-7.

Abstract

Purpose: To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin.

Methods: A 10-year-old girl with juxtapapillary CNV in the right eye and juxtapapillary and juxtafoveal CNV in the left eye associated with OND underwent PDT with verteporfin in both eyes.

Results: Visual acuity increased from 20/160 to 20/25 in the right eye and from 20/1000 to 20/25 in the left eye after two sessions of PDT and 2 years of follow-up. CNV showed no leakage after two PDT sessions in both eyes and no recurrence was observed.

Conclusions: Subfoveal CNV is an uncommon complication of OND and excellent anatomic and functional results can be obtained with PDT.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Choroidal Neovascularization / complications
  • Choroidal Neovascularization / drug therapy*
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Optic Disk Drusen / complications
  • Optic Disk Drusen / drug therapy*
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use*
  • Porphyrins / therapeutic use*
  • Tomography, Optical Coherence
  • Treatment Outcome
  • Verteporfin
  • Visual Acuity

Substances

  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin