Comparative and evolutionary genomics of Yersinia pestis

Microbes Infect. 2004 Nov;6(13):1226-34. doi: 10.1016/j.micinf.2004.08.002.

Abstract

Yersinia pestis is the causative agent of plague, causing three human plague pandemics in history. Comparative and evolutionary genomics of Y. pestis are extensively discussed in this review. Understanding the genomic variability and the adaptive evolution of Y. pestis from the genomic point of view will contribute greatly to plague detection, identification, control and prevention.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Biological
  • Biological Evolution*
  • Genetic Variation
  • Genome, Bacterial*
  • Genomics*
  • Yersinia pestis / genetics*
  • Yersinia pestis / physiology*
  • Yersinia pseudotuberculosis / classification
  • Yersinia pseudotuberculosis / genetics