Magnetic resonance imaging in Posterior Reversible Encephalopathy Syndrome: report of three cases and review of literature

Arch Gynecol Obstet. 2005 Jan;271(1):79-85. doi: 10.1007/s00404-004-0622-1. Epub 2004 Oct 9.

Abstract

Introduction: Eclampsia is one of the main causes of Posterior Reversible Encephalopathy Syndrome (PRES) a recent clinico-neuroradiological entity represented by characteristic MR findings of a symmetric bilateral subcortical/cortical hyperintensity in T2-weighted images, more often in parieto-occipital lobes, accompanied by clinical neurological alterations. Neuroradiological and clinical alterations are commonly completely reversible although ischemic evolution has been described. The pathophysiology is still a matter of debate. Specific magnetic resonance (MR) techniques, such as FLAIR (fluid attenuated inversion recovery) and DWI (diffusion weighted images) sequences, have improved the ability to detect subcortical/cortical lesions and helped to clarify the underlying pathophysiological mechanism of cerebrovascular involvement, which results important for an appropriate therapeutic decision.

Case report and discussion: We report the MR imaging findings of three patients with eclampsia and PRES as well as a careful review of literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Brain Diseases / diagnosis
  • Brain Diseases / etiology
  • Brain Edema / diagnosis
  • Brain Edema / etiology
  • Diagnosis, Differential
  • Eclampsia*
  • Female
  • Humans
  • Hypertensive Encephalopathy / diagnosis*
  • Hypertensive Encephalopathy / etiology
  • Magnetic Resonance Imaging / methods*
  • Pregnancy
  • Pregnancy Outcome
  • Syndrome