Gastric emptying in very-low-birth-weight infants treated with nasal continuous positive airway pressure

J Pediatr. 2004 Oct;145(4):508-10. doi: 10.1016/j.jpeds.2004.06.030.

Abstract

Objective: Nasal continuous positive airway pressure (NCPAP) is frequently used for prolonged periods in very low birth weight infants. We asked if NCPAP affects gastric emptying.

Study design: Preterm newborn infants (n = 16) with a mean body weight of 935 g (SD, 155) and a mean gestational age of 27.7 weeks (SD, 1.9) were treated with NCPAP and fed by orogastric tube. A comparison group of 20 newborn infants with a mean body weight of 1090 grams (SD, 130) and a mean gestational age of 28.2 weeks (SD, 1.2) were not receiving NCPAP. All newborn infants received a milk formula containing 81 kcal/dL given in similar quantities. The antral cross-sectional area was measured by means of an ultrasound technique.

Results: Mean half-time of antral cross-sectional area was 28 minutes (SD, 12) in the NCPAP group and 40 minutes (SD, 17) in the comparison group ( P < .05). There were no differences in gastrointestinal complications between the two groups.

Conclusions: The gastric emptying time was shorter for newborn infants treated with NCPAP.

MeSH terms

  • Case-Control Studies
  • Continuous Positive Airway Pressure*
  • Enteral Nutrition*
  • Female
  • Gastric Emptying / physiology*
  • Humans
  • Infant Formula / administration & dosage
  • Infant, Newborn
  • Infant, Very Low Birth Weight / physiology*
  • Male
  • Prospective Studies