NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

Gut. 2004 Nov;53(11):1558-60. doi: 10.1136/gut.2004.043307.
No abstract available

Publication types

  • Comment
  • Review

MeSH terms

  • Crohn Disease / genetics*
  • Crohn Disease / immunology
  • Humans
  • Immunity, Mucosal
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Mutation / immunology*
  • Nod2 Signaling Adaptor Protein
  • Paneth Cells / immunology*
  • alpha-Defensins / biosynthesis

Substances

  • Intracellular Signaling Peptides and Proteins
  • NOD2 protein, human
  • Nod2 Signaling Adaptor Protein
  • alpha-Defensins