New method for detection of Mycobacterium tuberculosis Direct Test inhibitors in clinical specimens

A Sloutsky; L L Han; B G Werner

doi:10.1016/j.diagmicrobio.2004.06.012

New method for detection of Mycobacterium tuberculosis Direct Test inhibitors in clinical specimens

Diagn Microbiol Infect Dis. 2004 Oct;50(2):109-11. doi: 10.1016/j.diagmicrobio.2004.06.012.

Authors

A Sloutsky¹, L L Han, B G Werner

Affiliation

¹ Massachusetts State Laboratory Institute, Boston, MA 02130, USA. alex.sloutsky@state.ma.us

PMID: 15474319
DOI: 10.1016/j.diagmicrobio.2004.06.012

Abstract

Existing protocols for the detection of Mycobacterium tuberculosis Direct Test (MDT) inhibitors require substantial quantities of specimen and cannot distinguish Mycobacterium tuberculosis complex from other mycobacteria if inhibitors are present. We describe a preliminary evaluation of a simple and practical protocol for MTD inhibitor testing that circumvents these difficulties.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Bacteriological Techniques*
Female
Humans
Male
Mycobacterium tuberculosis / isolation & purification*
RNA, Bacterial / analysis
Retrospective Studies
Sampling Studies
Sensitivity and Specificity
Specimen Handling

Substances

RNA, Bacterial