Abstract
With proper activation of the leaving group, sulfur mustards react with Grignard reagents with neighboring group participation of the sulfur atom. 2,6-Dichloro-9-thiabicyclo[3.3.1]nonane is especially useful in this regard, providing clean reactivity with organomagnesium nucleophiles on a topologically constrained scaffold.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Crystallography, X-Ray
-
Indicators and Reagents / chemistry
-
Molecular Structure
-
Mustard Compounds / chemical synthesis*
-
Mustard Compounds / chemistry
-
Oxidation-Reduction
-
Stereoisomerism
-
Sulfur / chemistry*
Substances
-
Indicators and Reagents
-
Mustard Compounds
-
Sulfur