The clinical course of thrombohemorrhagic complications was studied in 56 patients, aged 18 to 38, with sepsis, which developed due to obstetric and gynecologic processes on days 1, 3, 5, 7 and 10 after surgery. The patients were treated, 1999-2003, at the obstetric intensive-care and consultation center, MUZA Maternity Hospital No. 1, Krasnoyarsk. The coagulation, anti-coagulation and fibrinolytic chains of the coagulation cascade and vascular-thrombotic hemostasis were dynamically evaluated. Thrombohemorrhagic complications in severe sepsis and septic shock manifested themselves as hypercoagulation stage in 52% of observations. The hemostasis correction does not only require the elimination of changes in the hemocoagulation system but also the intensive care of the present systemic dysfunctions.