A conventional route for the synthesis of new oxazolidin-2-one derivatives with beta-aminoalanines

Fumiko Fujisaki; Nobuhiro Abe; Kunihiro Sumoto

doi:10.1248/cpb.52.1238

A conventional route for the synthesis of new oxazolidin-2-one derivatives with beta-aminoalanines

Chem Pharm Bull (Tokyo). 2004 Oct;52(10):1238-41. doi: 10.1248/cpb.52.1238.

Authors

Fumiko Fujisaki¹, Nobuhiro Abe, Kunihiro Sumoto

Affiliation

¹ Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

PMID: 15467244
DOI: 10.1248/cpb.52.1238

Abstract

A conventional new route to the novel oxazolidin-2-one derivatives (3a-f) having two substituents on N-3 and C-4 in the oxazolidin-2-one ring was established with racemic beta-aminoalanine derivatives (1) as the key starting materials.

MeSH terms

Magnetic Resonance Spectroscopy
Molecular Structure
Oxazolidinones / chemical synthesis*
Oxazolidinones / chemistry
Stereoisomerism
beta-Alanine / analogs & derivatives*
beta-Alanine / chemical synthesis*
beta-Alanine / chemistry

Substances

Oxazolidinones
beta-Alanine
2,3-diaminopropionic acid