Abstract
We report a woman with anti-Yo-associated cerebellar degeneration, severe eye movement abnormalities, and no evidence of malignancy after 3 years of extensive evaluation. The prominent neuro-ophthalmologic findings suggest brainstem involvement, which may be a novel manifestation of anti-Yo associated paraneoplastic syndrome.
MeSH terms
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Blotting, Western / methods
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Cerebellar Diseases / complications*
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Cerebellar Diseases / immunology
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DNA-Binding Proteins / immunology*
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Female
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Humans
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Middle Aged
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Neoplasm Proteins / immunology*
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Nerve Tissue Proteins
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Ocular Motility Disorders / etiology*
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Paraneoplastic Syndromes / complications*
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Paraneoplastic Syndromes / immunology
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Retrospective Studies
Substances
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CDR2 protein, human
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DNA-Binding Proteins
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Neoplasm Proteins
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Nerve Tissue Proteins