With the aging of society in Japan, the figure of Parkinson's disease is gradually increasing and the percentage of patients with severe disease has also increased. Among intractable neurological diseases, the possibility of bed confinement is the highest for this disease. Therefore, in addition to appropriate control of the disease using anti-parkinsonism drugs, maintenance of QOL, rehabilitation, the daily life therapy and treatment at home are necessary in terms of long-term management. Treatment at home combined with persons who care for the patient and in cooperation with other welfare resources may improve the patient's QOL. In diseases that require long-term care such as Parkinson's disease, a comprehensive care management system should be established from the aspect of the patient's QOL.