Abstract
Treatment with the phytopreparation from papaya accelerated wound healing and reduced the severity of local inflammation in rats with burn wounds. The effect of this phytopreparation can be related to an increase in the effectiveness of intracellular bacterial killing by tissue phagocytes due to the inhibition of bacterial catalase. Antioxidant activity of the preparation decreases the risk of oxidative damage to tissues.
MeSH terms
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Animals
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Anti-Inflammatory Agents / therapeutic use
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Antioxidants / therapeutic use
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Burns / drug therapy*
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Carica / chemistry*
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Catalase / metabolism
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Humans
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Inflammation / drug therapy
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Male
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Phytotherapy*
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Plant Preparations / therapeutic use*
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Rats
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Rats, Wistar
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Reactive Oxygen Species / metabolism
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Staphylococcus aureus / immunology
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Wound Healing*
Substances
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Anti-Inflammatory Agents
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Antioxidants
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Plant Preparations
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Reactive Oxygen Species
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Catalase