Cerebral metastasis from a primary adenocarcinoma of the fallopian tube

Gynecol Oncol. 2004 Oct;95(1):260-3. doi: 10.1016/j.ygyno.2004.06.036.

Abstract

Background: Primary adenocarcinoma of the fallopian tube is a rare disease, and cerebral metastasis from this tumor is an extremely rare event.

Case: A 61-year-old female, who had been thought to be in a disease-free state after the initial treatment for stage IIIc fallopian tube adenocarcinoma, presented with severe headache, dizziness, nausea, and vomiting. Brain CT and MRI revealed solitary metastatic lesion in the cerebrum, which was the only site of recurrence. It was removed surgically, followed by platinum-based combination chemotherapy, and a clinical remission was achieved for 36 months.

Conclusion: Attention should be paid to the possibility of cerebral metastasis in patients who develop neurogenic signs and symptoms. Prolonged survival could be achieved with aggressive treatment containing surgical debulking and adjuvant chemotherapy for solitary cerebral metastasis.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary*
  • Adenocarcinoma / surgery
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / surgery
  • Fallopian Tube Neoplasms / pathology*
  • Female
  • Humans
  • Middle Aged