Ability of troponin T to predict angiographic coronary artery disease in patients with chronic kidney disease

Am J Cardiol. 2004 Sep 15;94(6):834-6. doi: 10.1016/j.amjcard.2004.05.075.

Abstract

Association between angiographic coronary artery disease and cardiac troponin T levels has been observed in patients with normal kidney function; however, this association remains unsettled in patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD). Over a 12-month period we retrospectively reviewed coronary angiograms (CAs) performed in 194 hospitalized patients with presumed acute myocardial injury. About 50% of the ESRD and 30% of the CKD patients had normal CAs. Troponin T levels significantly correlated with CAs in patients with normal kidney function (r = 0.4, p = 0.005) but not in ESRD and CKD patients (r = 0.2, p = NS, respectively).

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Coronary Angiography
  • Coronary Disease / blood*
  • Coronary Disease / diagnostic imaging*
  • Female
  • Humans
  • Kidney Failure, Chronic / blood
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Troponin T / blood*

Substances

  • Troponin T