Multivessel variant angina unresponsive to urapidil

Acta Cardiol. 2004 Aug;59(4):439-43. doi: 10.2143/AC.59.4.2005212.

Abstract

We present a case of variant angina complicated by recurrent sudden cardiac death. During coronary angiography a diffuse 3-vessel vasoconstriction was observed progressing to a more severe vasoconstriction in the mid LAD. Intracoronary administration of urapidil did not reverse the vasoconstriction of the LAD; instead an occlusive vasospasm occurred accompanied by marked ischaemia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angina Pectoris, Variant / diagnosis
  • Angina Pectoris, Variant / physiopathology*
  • Angina Pectoris, Variant / therapy*
  • Angioplasty, Balloon, Coronary
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / therapy
  • Coronary Angiography
  • Coronary Vasospasm / diagnosis
  • Coronary Vasospasm / physiopathology
  • Coronary Vasospasm / therapy
  • Coronary Vessels / drug effects*
  • Coronary Vessels / physiopathology*
  • Coronary Vessels / surgery
  • Death, Sudden, Cardiac / pathology
  • Echocardiography
  • Electrocardiography
  • Electrophysiologic Techniques, Cardiac
  • Humans
  • Male
  • Piperazines / therapeutic use*
  • Vasoconstriction / drug effects
  • Vasodilator Agents / therapeutic use*

Substances

  • Piperazines
  • Vasodilator Agents
  • urapidil