Abstract
Objectives:
Left main coronary artery dimensions were evaluated in patients with and without arterial hypertension, in the presence of coronary artery disease, and correlated to left ventricular mass.
Methods and results:
Intracoronary ultrasound was performed in 25 patients (pts) with coronary artery disease and hypertension (+HTN) and in 25 pts with coronary artery disease only (-HTN). Maximal left main dimensions and left ventricular mass index (LVMI) were measured. +HTN pts had greater LVMI compared to -HTN, (+HTN = 183 +/- 17 g/m2 vs. -HTN = 82 +/- 22 g/m2, p < 0.0001), while maximal left main vessel area was similar (25.99 +/- 5.01 mm2 vs. 25.62 +/- 3.3 mm2, p = 0.8). No correlation was found between LVMI and left main vessel area in + HTN.
Conclusions:
Pts with +HTN despite the increased LVMI do not manifest increased LM dimensions. This may affect mid-term clinical outcome.
Publication types
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Comparative Study
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Evaluation Study
MeSH terms
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Adrenergic beta-Antagonists / therapeutic use
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Aged
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Angiotensin-Converting Enzyme Inhibitors / therapeutic use
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Arteries / diagnostic imaging*
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Arteries / pathology*
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Blood Pressure / drug effects
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Calcium Channel Blockers / therapeutic use
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Coronary Angiography
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Coronary Artery Disease / diagnosis*
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Coronary Artery Disease / drug therapy
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Coronary Artery Disease / epidemiology
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Coronary Vessels / diagnostic imaging*
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Coronary Vessels / pathology*
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Diastole / drug effects
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Female
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Follow-Up Studies
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Humans
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Hypertension / diagnosis*
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Hypertension / drug therapy
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Hypertension / physiopathology
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Hypertrophy, Left Ventricular / diagnosis*
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Hypertrophy, Left Ventricular / drug therapy
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Hypertrophy, Left Ventricular / epidemiology
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Male
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Middle Aged
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Nitroglycerin / therapeutic use
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Observer Variation
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Statistics as Topic
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Systole / drug effects
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Treatment Outcome
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Tunica Intima / diagnostic imaging
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Tunica Intima / pathology
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Ultrasonography, Interventional*
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Vasodilator Agents / therapeutic use
Substances
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Adrenergic beta-Antagonists
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Angiotensin-Converting Enzyme Inhibitors
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Calcium Channel Blockers
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Vasodilator Agents
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Nitroglycerin