Gemcitabine and oxaliplatinum: an effective regimen in a patient with progressive refractory mantle cell lymphoma

Leuk Lymphoma. 2004 Jun;45(6):1289-91. doi: 10.1080/1042819032000159852.

Abstract

We report here a 68-year-old man with progressive refractory Mantle cell Lymphoma stage IV-A, treated with different chemotherapeutic drugs. With no therapeutic options we decided to treat him with oxaliplatinum-gemcitabine regimen, based on the proven efficacy and synergy of these drugs in other tumors and lymphomas. Treatment was well tolerated and patient achieved a maintained complete remission with 6 months of follow up. We consider that this may be a salvage therapeutic option for patients with mantle cell lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives*
  • Disease Progression
  • Gemcitabine
  • Humans
  • Lymphoma, Mantle-Cell / drug therapy*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / drug therapy*
  • Organoplatinum Compounds / administration & dosage
  • Oxaliplatin
  • Salvage Therapy

Substances

  • Organoplatinum Compounds
  • Oxaliplatin
  • Deoxycytidine
  • Gemcitabine