Development of a polymer stent with shape memory effect as a drug delivery system

J Mater Sci Mater Med. 2003 Feb;14(2):109-12. doi: 10.1023/a:1022007510352.

Abstract

The article presents a new concept for vascular endoprothesis (stent). Almost all commercially available stents are made of metallic materials. A common after effect of stent implantation is restenosis. Several studies on metal stents coated with drug show, that the use of a drug delivery system may reduce restenosis. The purpose of this work is to develop a new stent for the drug delivery application. The shape memory properties of thermoplastic polyurethane allow to design a new fully polymeric self-expandable stent. The possibility to use the stent as a drug delivery system is described.