Abstract
The structure of a new dibenzodiazepine alkaloid, diazepinomicin (1), isolated from the culture of a marine actinomycete of the genus Micromonospora was characterized using spectroscopic methods. Diazepinomicin represents a unique molecular class composed of a dibenzodiazepine core linked to a farnesyl side chain.
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Dibenzazepines / chemistry
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Dibenzazepines / isolation & purification*
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Dibenzazepines / pharmacology
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Gram-Positive Bacteria / drug effects
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Japan
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Microbial Sensitivity Tests
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Micromonospora / chemistry*
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
Substances
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Alkaloids
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Anti-Bacterial Agents
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Dibenzazepines
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diazepinomicin