Stereoselective synthesis of (+)-boronolide and its 8-epimer

Org Biomol Chem. 2004 Aug 21;2(16):2305-10. doi: 10.1039/B406397J. Epub 2004 Jul 23.

Abstract

Starting from readily available carbohydrates the synthesis of 8-epi-(+)-boronolide 19 and (+)-boronolide was achieved with diastereoselective propargylation of alpha-oxygenated aldehyde as a key step.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Lactones / chemical synthesis*
  • Lactones / chemistry*
  • Lamiaceae / chemistry
  • Molecular Structure
  • Stereoisomerism

Substances

  • Lactones
  • boronolide