Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory

J Clin Microbiol. 2004 Aug;42(8):3850-2. doi: 10.1128/JCM.42.8.3850-3852.2004.

Abstract

We report a prospective comparison of human immunodeficiency virus type 1 testing by enzyme immunoassay and Western blot with four rapid tests of 486 subjects performed in rural Kenya. Rapid test sensitivity was 100%. Specificity ranged from 99.1 to 100%. Combined use of two Food and Drug Administration-approved rapid tests yielded a single false-positive result.

Publication types

  • Comparative Study

MeSH terms

  • Acquired Immunodeficiency Syndrome / diagnosis*
  • Acquired Immunodeficiency Syndrome / epidemiology
  • Blotting, Western / methods
  • HIV Infections / diagnosis*
  • HIV Infections / epidemiology
  • HIV-1 / isolation & purification*
  • Humans
  • Immunoenzyme Techniques / methods
  • Kenya / epidemiology
  • Mass Screening / methods
  • Predictive Value of Tests
  • Prevalence
  • Reproducibility of Results
  • Sensitivity and Specificity