High lactate dehydrogenase isoenzyme 1 in a patient with malignant germ cell tumor is attributable to aberrant methylation of the LDHA gene

Clin Chem. 2004 Oct;50(10):1826-8. doi: 10.1373/clinchem.2004.037739. Epub 2004 Aug 5.

Authors

Jinko Ishikawa¹, Terumi Taniguchi, Hitomi Higashi, Katsutoshi Miura, Kazuya Suzuki, Akihiro Takeshita, Masato Maekawa

Affiliation

¹ Department of Laboratory Medicine, Hamamatsu University School of Medicine, 431-3192, Japan.

PMID: 15297388
DOI: 10.1373/clinchem.2004.037739

No abstract available

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Carcinoma, Embryonal / complications
Carcinoma, Embryonal / enzymology
Endodermal Sinus Tumor / complications
Endodermal Sinus Tumor / enzymology
Germinoma / complications
Germinoma / enzymology*
Humans
Isoenzymes / blood
Isoenzymes / genetics
Isoenzymes / metabolism*
L-Lactate Dehydrogenase / blood
L-Lactate Dehydrogenase / genetics
L-Lactate Dehydrogenase / metabolism*
Male
Mediastinal Neoplasms / complications
Mediastinal Neoplasms / enzymology
Methylation
Mutation
Rhabdomyosarcoma / complications
Rhabdomyosarcoma / enzymology
Teratoma / complications
Teratoma / enzymology
Testicular Neoplasms / complications
Testicular Neoplasms / enzymology*

Substances

Isoenzymes
L-Lactate Dehydrogenase
lactate dehydrogenase 1