[Agonists and antagonists of mineralocorticoids. The relation between structure and activity]

J Fagart; G M Pinon; M E Rafestin-Oblin

doi:10.1016/j.ancard.2004.02.018

[Agonists and antagonists of mineralocorticoids. The relation between structure and activity]

Ann Cardiol Angeiol (Paris). 2004 Jun;53(3):154-7. doi: 10.1016/j.ancard.2004.02.018.

[Article in French]

Authors

J Fagart¹, G M Pinon, M E Rafestin-Oblin

Affiliation

¹ Inserm 478, faculté de médecine Xavier-Bichat, 16, rue Henri-Huchard, 75780 Paris cedex 18, France.

PMID: 15291173
DOI: 10.1016/j.ancard.2004.02.018

Abstract

The mechanism of action of aldosterone and its links with the mineralocorticoids receptor (MR) are described. The physiologic importance of the MR structure is emphasized, in relation with the preferential activation of the receptor by aldosterone.

Publication types

English Abstract
Review

MeSH terms

Aldosterone / pharmacology*
Humans
Ligands
Mineralocorticoids / pharmacology*
Receptors, Mineralocorticoid / physiology*
Structure-Activity Relationship

Substances

Ligands
Mineralocorticoids
Receptors, Mineralocorticoid
Aldosterone