The hand in metastatic disease and acral manifestations of paraneoplastic syndromes

Radford J Hayden; Lawrence G Sullivan; Peter J L Jebson

doi:10.1016/j.hcl.2004.03.010

The hand in metastatic disease and acral manifestations of paraneoplastic syndromes

Hand Clin. 2004 Aug;20(3):335-43, vii. doi: 10.1016/j.hcl.2004.03.010.

Authors

Radford J Hayden¹, Lawrence G Sullivan, Peter J L Jebson

Affiliation

¹ Division of Hand, Elbow, and Microsurgery, Department of Orthopaedic Surgery, University of Michigan Medical Center, 2098 South Main Street, Ann Arbor, MI 48103, USA. rhayden@umich.edu

PMID: 15275692
DOI: 10.1016/j.hcl.2004.03.010

Abstract

Metastatic tumors to the hand and wrist are rare, accounting for approximately 0.1% of all metastatic lesions to the skeleton. The biochemically mediated pathways of bone metastases, the location of the hand at the distal extremity, and the small amount of marrow in the bones of the hand and wrist account for the low prevalence of acrometastases. More rarely, hand dermatologic and soft tissue changes of paraneoplastic syndromes herald an occult malignancy.

Publication types

Review

MeSH terms

Bone Neoplasms / diagnosis
Bone Neoplasms / pathology
Bone Neoplasms / physiopathology
Bone Neoplasms / secondary*
Bone Neoplasms / therapy
Breast Neoplasms / pathology
Curettage
Fingers
Hand*
Humans
Kidney Neoplasms / pathology
Lung Neoplasms / pathology
Magnetic Resonance Imaging
Paraneoplastic Syndromes*
Physical Examination
Prognosis
Tomography, X-Ray Computed