Five new Ocotillone-type saponins from Gynostemma pentaphyllum

J Nat Prod. 2004 Jul;67(7):1147-51. doi: 10.1021/np034018+.

Abstract

Five new ocotillone-type saponins, gynosides A-E (1-5), along with 10 known dammarane-type saponins, were isolated from the aerial parts of Gynostemma pentaphyllum. The structures of these new compounds were determined by NMR analysis and acid hydrolysis. The structure and stereochemistry of gynoside A (1) were confirmed by X-ray crystallography.

MeSH terms

  • Crystallography, X-Ray
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification*
  • Gynostemma / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Saponins / chemistry*
  • Saponins / isolation & purification*

Substances

  • Drugs, Chinese Herbal
  • Saponins
  • gynoside A