Fluorescent GTP-sensing in aqueous solution of physiological pH

J Am Chem Soc. 2004 Jul 28;126(29):8892-3. doi: 10.1021/ja0492440.

Abstract

A new water-soluble imidazolium anthracene derivative not only differentiates two structurally similar compounds GTP and ATP but also acts as potential fluorescent chemosensors (as a quencher and an enhancer, respectively) for GTP and ATP in 100% aqueous solution (pH = 7.4, 10 mM HEPES).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / analysis
  • Adenosine Triphosphate / chemistry
  • Anthracenes / chemical synthesis
  • Anthracenes / chemistry
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Guanosine Triphosphate / analysis*
  • Guanosine Triphosphate / chemistry
  • Hydrogen-Ion Concentration
  • Imidazoles / chemical synthesis
  • Imidazoles / chemistry*
  • Imidazoline Receptors
  • Kinetics
  • Models, Molecular
  • Receptors, Drug / chemistry
  • Solutions
  • Spectrometry, Fluorescence
  • Substrate Specificity
  • Water / chemistry

Substances

  • Anthracenes
  • Fluorescent Dyes
  • Imidazoles
  • Imidazoline Receptors
  • Receptors, Drug
  • Solutions
  • Water
  • Guanosine Triphosphate
  • Adenosine Triphosphate