Much has been written in the sports medicine literature regarding return to competition following anterior cruciate ligament reconstruction; however, little scientific work has been done regarding the return to competition following meniscal surgery or cartilage surgery. This article reviews the basic science of meniscal surgery and cartilage surgery in an attempt to promote rational rehabilitative protocols rooted in scientific investigation. A twofold approach is used. One approach is from a biologic standpoint; that is, when are the repaired tissues healed enough to withstand physiologic activity? The second approach is from a rehabilitative standpoint; when is the patient strong enough to play without recurrent injury?