Necessity's sharp pinch

Kristin T Chun; Mark G Goebl

doi:10.1016/j.molcel.2004.07.008

Necessity's sharp pinch

Mol Cell. 2004 Jul 23;15(2):166-8. doi: 10.1016/j.molcel.2004.07.008.

Authors

Kristin T Chun¹, Mark G Goebl

Affiliation

¹ Department of Biochemistry and Molecular Biology, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis 46202, USA.

PMID: 15260966
DOI: 10.1016/j.molcel.2004.07.008

Abstract

In a recent issue of Cell, Hughes and coworkers (Mnaimneh et al., 2004) provide a great leap forward in the analysis of essential yeast genes by constructing a strain set that expresses each essential gene from a tetracycline-regulatable promoter.

Publication types

Editorial

MeSH terms

Gene Expression Regulation, Fungal / drug effects*
Genes, Essential*
Genes, Fungal / genetics*
Promoter Regions, Genetic / genetics*
Protein Processing, Post-Translational
Protein Synthesis Inhibitors / pharmacology*
Saccharomyces cerevisiae / drug effects
Saccharomyces cerevisiae / genetics
Saccharomyces cerevisiae / metabolism
Saccharomyces cerevisiae Proteins / genetics
Saccharomyces cerevisiae Proteins / metabolism
Tetracycline / pharmacology*
Transcription, Genetic

Substances

Protein Synthesis Inhibitors
Saccharomyces cerevisiae Proteins
Tetracycline