Abstract
An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsoralen.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Angelica*
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification
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Enzyme Inhibitors / pharmacology*
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Furocoumarins / chemistry
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Furocoumarins / isolation & purification
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Furocoumarins / pharmacology*
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Monophenol Monooxygenase / antagonists & inhibitors*
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Monophenol Monooxygenase / metabolism
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plant Roots
Substances
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Enzyme Inhibitors
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Furocoumarins
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Plant Extracts
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Monophenol Monooxygenase