Abstract
Redox active cyclopeptides Fc[CSA]2 (5), Fc[Gly-CSA]2 (6), Fc[Ala-CSA]2 (7), Fc[Val-CSA](2) and Fc[Leu-CSA]2 (9) (CSA = cysteamine) which are formed by the reaction of ferrocenedicarboxylic acid with peptide cystamines at high dilutions. These systems exhibit H-bonding involving the amide NH in solution as shown by their temperature dependent NMR spectra. With the exception of 5, the ferrocene macrocycles display intramolecular N...O cross-ring H-bonding in the solid state involving the amino acids proximal to the ferrocene.
MeSH terms
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Amides / chemistry
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Amino Acids / chemistry
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Crystallography, X-Ray
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Cystamine / chemistry
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Electrochemistry / methods
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Ferrous Compounds / chemical synthesis
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Ferrous Compounds / chemistry*
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Heterocyclic Compounds / chemical synthesis
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Heterocyclic Compounds / chemistry*
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Magnetic Resonance Spectroscopy / methods
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Metallocenes
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Molecular Structure
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Oxidation-Reduction
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Peptides / chemical synthesis
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Peptides / chemistry*
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Temperature
Substances
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Amides
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Amino Acids
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Ferrous Compounds
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Heterocyclic Compounds
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Metallocenes
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Peptides
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Cystamine
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ferrocene