Dental erosion, gastro-oesophageal reflux disease and saliva: how are they related?

J Dent. 2004 Aug;32(6):489-94. doi: 10.1016/j.jdent.2004.03.004.

Abstract

Aims: The purpose of this study was to assess the prevalence of tooth wear, symptoms of reflux and salivary parameters in a group of patients referred for investigation of gastro-oesophageal reflux disease (GORD) compared with a group of control subjects.

Materials and methods: Tooth wear, stimulated salivary flow rate and buffering capacity and symptoms of GORD were assessed in patients attending an Oesophageal Laboratory. Patients had manometry and 24-h pH tests, which are the gold standard for the diagnosis of GORD. Tooth wear was assessed using a modification of the Smith and Knight tooth wear index. The results were compared to those obtained from a group of controls with no symptoms of GORD.

Results: Patients with symptoms of GORD and those subsequently diagnosed with GORD had higher total and palatal tooth wear (p<0.05). The buffering capacity of the stimulated saliva from the control subjects was greater than patients with symptoms of GORD (p<0.001). Patients with hoarseness had a lower salivary flow rate compared with those with no hoarseness.

Conclusions: Tooth wear involving dentine was more prevalent in patients complaining of symptoms of GORD and those diagnosed as having GORD following 24-h pH monitoring than controls. Patients had poorer salivary buffering capacity than control subjects. Patients complaining of hoarseness had lower salivary flow rate than controls.

MeSH terms

  • Adult
  • Aged
  • Buffers
  • Case-Control Studies
  • Female
  • Gastroesophageal Reflux / complications*
  • Hoarseness / etiology
  • Humans
  • Hydrogen-Ion Concentration
  • Male
  • Middle Aged
  • Saliva / chemistry
  • Saliva / metabolism*
  • Secretory Rate
  • Tooth Erosion / etiology*

Substances

  • Buffers