Pertussis. Presentation, investigation and management

Aust Fam Physician. 2004 May;33(5):317-9.

Abstract

Background: Pertussis (whooping cough) is a highly infectious, preventable disease, which causes significant morbidity and mortality.

Objective: This article discusses the presentations, investigations and management of cases and their contacts.

Discussion: Maternal antibody does not confer protection to the infant so babies are particularly at risk of infection and complications until they have completed the primary course of vaccinations at 2, 4 and 6 months of age. Diagnosis is primarily clinical, but can be confirmed with immunofluorescence on nasopharyngeal aspirate or nasal swab. Recent changes to the Australian Standard Vaccination Schedule include the removal of the 18 month dose of DTPa and the addition of an adult formulation booster vaccination at 15-17 years of age.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Australia
  • Bordetella pertussis / isolation & purification
  • Child
  • Child, Preschool
  • Family Practice / methods*
  • Family Practice / standards
  • Humans
  • Immunization Schedule
  • Infant
  • Patient Isolation / standards
  • Pertussis Vaccine / therapeutic use
  • Practice Guidelines as Topic
  • Whooping Cough / diagnosis*
  • Whooping Cough / drug therapy
  • Whooping Cough / microbiology
  • Whooping Cough / prevention & control*

Substances

  • Anti-Bacterial Agents
  • Pertussis Vaccine