Abstract
The 3' untranslated region (3' UTR) of the genome of the severe acute respiratory syndrome coronavirus can functionally replace its counterpart in the prototype group 2 coronavirus mouse hepatitis virus (MHV). By contrast, the 3' UTRs of representative group 1 or group 3 coronaviruses cannot operate as substitutes for the MHV 3' UTR.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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3' Untranslated Regions / genetics*
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Animals
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Base Sequence
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Enhancer Elements, Genetic*
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Genome, Viral
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Humans
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Mice
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Molecular Sequence Data
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Murine hepatitis virus / genetics*
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Recombination, Genetic*
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Severe acute respiratory syndrome-related coronavirus / genetics*
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Virus Replication*