A new ecdysteroid with unique 9beta-OH and four other ecdysteroids from Silene italica ssp. nemoralis

András Simon; Zita Pongrácz; Gábor Tóth; Marianna Mák; Imre Máthé; Mária Báthori

doi:10.1016/j.steroids.2004.03.009

A new ecdysteroid with unique 9beta-OH and four other ecdysteroids from Silene italica ssp. nemoralis

Steroids. 2004 Jun;69(6):389-94. doi: 10.1016/j.steroids.2004.03.009.

Authors

András Simon¹, Zita Pongrácz, Gábor Tóth, Marianna Mák, Imre Máthé, Mária Báthori

Affiliation

¹ Institute for General and Analytical Chemistry, Budapest University of Technology and Economics, Budapest, Szt. Gellért tér 4, H-1111 Hungary.

PMID: 15219788
DOI: 10.1016/j.steroids.2004.03.009

Abstract

A new natural ecdysteroid, 9beta,20-dihydroxyecdysone (1) and four related compounds 5alpha-20-hydroxyecdysone (2), 5alpha-2-deoxy-integristerone A (3), integristerone A (4) and 22-deoxy-integristerone A (5) were isolated from the herb of Silene italica ssp. nemoralis. Compound 1 is the C-9 epimer of the known 9alpha,20-dihydroxyecdysone (6) and represents a peculiar steroid skeleton. The structures of the compounds were elucidated by 1D and 2D NMR, IR and MS spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Ecdysteroids / analogs & derivatives*
Ecdysteroids / chemistry*
Ecdysteroids / isolation & purification
Molecular Conformation
Silene / chemistry*

Substances

Ecdysteroids