Electronic detection of the enzymatic degradation of starch

Org Lett. 2004 Jun 24;6(13):2089-92. doi: 10.1021/ol0495826.

Abstract

[reaction: see text] The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amylopectin / chemistry
  • Amylose / chemistry
  • Carbohydrate Sequence
  • Glucan 1,4-alpha-Glucosidase / chemistry
  • Glucan 1,4-alpha-Glucosidase / metabolism*
  • Microscopy, Atomic Force
  • Molecular Sequence Data
  • Nanotubes, Carbon
  • Starch / chemistry
  • Starch / metabolism*
  • Transistors, Electronic*

Substances

  • Nanotubes, Carbon
  • Starch
  • Amylose
  • Amylopectin
  • Glucan 1,4-alpha-Glucosidase