Cerebral astroblastoma

Acta Neurochir (Wien). 2004 Jun;146(6):629-33. doi: 10.1007/s00701-004-0230-7. Epub 2004 Apr 13.

Abstract

Background: Astroblastoma is a rare glial tumour about which little is known.

Method: We report a case of cerebral high grade astroblastoma and discuss the clinical, histopathological, surgical, radiological and prognostic features of this tumour, in the light of the pertinent literature.

Result: Present patient had an initial histological diagnosis of glioblastoma multiforme. Three years later an histological reevaluation was performed and revealed a high grade astroblastoma. Our patient underwent surgical removal and radiotherapy; five years after the operation he is alive and without evidence of recurrence.

Interpretation: Classification and histogenesis of this tumour is still debated. The lack of a clinicopathological correlation makes the prognosis of this tumour unpredictable. The optimal management is not defined, but total resection and post-operative radiotherapy seem to be the effective means to treat the astroblastoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / pathology
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / surgery*
  • Combined Modality Therapy
  • Cranial Irradiation
  • Diagnosis, Differential
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neoplasms, Neuroepithelial / diagnosis
  • Neoplasms, Neuroepithelial / pathology
  • Neoplasms, Neuroepithelial / radiotherapy
  • Neoplasms, Neuroepithelial / surgery*
  • Radiotherapy, Adjuvant
  • Temporal Lobe / pathology
  • Temporal Lobe / surgery*
  • Tomography, X-Ray Computed